The most common form, ichthyosis vulgaris, occurs in 1 in 250 people, and typically occurs on the abdomen, arms and legs. Ichthyosis can appear anywhere on the skin. The skin becomes dry, scaly, thickened, may peel and is sometimes red and with small cracks. The skin can be painful when moving and it can become a skin infection.
Ichthyosis results from the epidermis being structured slightly differently than usual, usually with altered production of the substance filaggrin. Ichthyosis is usually a congenital condition that causes most people to have the skin changes from early childhood. The incidence of atopic eczema is increased with ichthyosis. On rare occasions, ichthyosis can occur as a result of other diseases and medicines. In severe forms of ichthyosis, a genetic test may be appropriate.
In mild cases, it is often sufficient to use a moisturiser, preferably containing carbamide, salicylic acid or fruit acids. Bathing in salt water, or with antibacterial creams can be helpful. In those with severe ichthyosis, treatment with tablets can provide relief. It is hoped that more effective treatment in the future.