Lipid necrobiosis (also known as necrobiosis lipoidica) is a relatively rare chronic skin disease. Diabetics make up the vast majority of cases (about 75%).
The skin disease is seen as characteristic, well-defined and reddish-brown spots with a central yellow color and/or ulceration. These spots can be round/oval in shape, possibly more irregular and confluent. At the edge of the skin changes, reddish areas of skin are often seen as a sign of active inflammation. Approximately 1/3 of cases develop ulcers.
Lipid necrobiosis is almost always localized to the front of the legs, often on both sides and quite symmetrically.
The condition is cosmetically unsightly, but rarely causes pain/suffering.
The cause is unknown. It has been speculated whether altered blood circulation in the skin's smallest blood vessels, a known complication of diabetes, may be of importance. Microscopic fat deposits can also be contributory.
The treatment of lipoid necrobiosis is challenging and has a variable effect. Often you don't reach your goal. The treatment options consist of cortisone cream/ointment/injection, other anti-inflammatory smear treatments and PUVA (light treatment). Good skin care and protection, as well as the use of compression stockings, are recommended.
Our dermatologists help people of all ages, from newborns to the elderly, with everything from simple skin changes to serious conditions.
Our dermatologists help people of all ages, from newborns to the elderly, with everything from simple skin changes to serious conditions.
